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Telukast 10mg 10pcs
Tablet Generic Name Montelukast Sodium 10 mg General Pharmaceuticals Ltd.
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✅ Description:
Indications
Montelukast Sodium is prescribed for the prevention and treatment of asthma.
Exercise-Induced Bronchoconstriction: Acute Prevention (EIB)
Allergic Rhinitis (AR) Symptom Relief: Seasonal & Perennial Allergic Rhinitis
Pharmacology
Montelukast inhibits the cysteinyl leukotriene receptor and is a selective and orally active leukotriene receptor antagonist (CysLT1). Arachidonic acid metabolism produces cysteinyl leukotrienes (LTC4, LTD4, LTE4), which are secreted by a variety of cells, including mast cells and eosinophils. The pathophysiology of asthma and allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, have been linked to cysteinyl leukotrienes and leukotriene receptor occupation, all of which contribute to the signs and symptoms of asthma.
Dosage & Administration
Adults & adolescents (15 years & older)-
Asthma & Allergic Rhinitis: 10 mg/day
Exercise-Induced Bronchoconstriction: 10 mg/day
Pediatric patients (6 to 14 years)-
Asthma & Allergic Rhinitis: 5 mg/day
Exercise-Induced Bronchoconstriction: 5 mg/day
Pediatric patients (6 months to 5 years)-
Asthma & Allergic Rhinitis: 4 mg/day
Exercise-Induced Bronchoconstriction: Not recommended
Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. For prevention of Acute prevention of Exercise-Induced Bronchoconstriction, a single dose should be taken at least 2 hours before exercise.
Interaction
When montelukast is combined with theophylline, prednisone, prednisolone, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative-hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, oral contraceptives, and CYP enzyme inducers, no dose adjustment is required.
With regard to food and others: With food and other conditions, bioavailability and other variables were not significantly noticed.
Contraindications
Patients who are hypersensitive to any component of Montelukast should avoid using it.
Side Effects
Diarrhoea, fever, gastrointestinal distress, headache, nausea, vomiting, skin responses, upper respiratory tract infection are all common symptoms.
Akathisia, anxiety, arthralgia, asthenia, aberrant behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, anomalous feeling, sleep disturbances are all uncommon symptoms.
Angioedema, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic problems, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor are all uncommon symptoms.
Pregnancy & Lactation
In pregnant women, there are no sufficient and well-controlled trials. Montelukast should only be used during pregnancy if it is absolutely necessary. Montelukast is a medication that is secreted in breast milk. When Montelukast is given to a nursing woman, vigilance should be observed.
Precautions & Warnings
Montelukast is not recommended for bronchospasm reversal in acute asthma attacks, including status asthmatic. Agitation, anger, anxiety, depression, disorientation, attention disturbances, dream abnormalities, hallucinations, insomnia, irritability, memory impairment, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremor are all neuropsychiatric occurrences.
Therapeutic Class
Leukotriene receptor antagonists.
Storage Conditions
Store in cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children.
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